GTF2H3 antibody (Middle Region)

Catalog No. ABIN2435858

Product Details anti-GTF2H3 Antibody

Target: GTF2H3 (General Transcription Factor IIH, Polypeptide 3, 34kD (GTF2H3))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Rabbit, Horse, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF2H3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KGQHTETLLA GSLAKALCYI HRMNKEVKDN QEMKSRILVI KAAEDSALQY

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GTF2H3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GTF2H3

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GTF2H3

Target: GTF2H3 (General Transcription Factor IIH, Polypeptide 3, 34kD (GTF2H3))

Alternative Name: GTF2H3 (GTF2H3 Products)

Synonyms: DDBDRAFT_0167192 antibody, DDBDRAFT_0230196 antibody, DDB_0167192 antibody, DDB_0230196 antibody, btf2 antibody, tfb4 antibody, tfiih antibody, 34kDa antibody, 5033417D07Rik antibody, BTF2 antibody, BTF2 p34 antibody, C730029A10 antibody, D5Ertd679e antibody, TFIIH antibody, GB12027 antibody, fc26a07 antibody, zgc:92759 antibody, wu:fc26a07 antibody, P34 antibody, TFB4 antibody, general transcription factor IIH, polypeptide 3 antibody, general transcription factor IIH subunit 3 antibody, gtf2h3 antibody, GTF2H3 antibody, Gtf2h3 antibody, LOC411231 antibody

Background: This gene encodes a member of the TFB4 family. The encoded protein is a subunit of the core-TFIIH basal transcription factor and localizes to the nucleus. The encoded protein is involved in RNA transcription by RNA polymerase II and nucleotide excision repair and associates with the Cdk-activating kinase complex. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 14.
Alias Symbols: P34, BTF2, TFB4, TFIIH
Protein Size: 200

Molecular Weight: 22 kDa

Gene ID: 2967

NCBI Accession: NM_001271866, NP_001258795

UniProt: Q13889

Pathways: DNA Damage Repair