PHLPP1 antibody

Catalog No. ABIN2451738

This Rabbit Polyclonal antibody specifically detects PHLPP1 in WB, ICC and IHC (p). It exhibits reactivity toward Human.

Quick Overview for PHLPP1 antibody (ABIN2451738)

Target: PHLPP1 (PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHLPP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PHLPP1 Antibody

Specificity: Detects the carboxy-terminal amino acids within the PDZ-binding domain of both the PHLPP1 alpha and beta isoforms. Detects the enzyme at around 150 kDa (alpha isoform) and 200 kDa (beta isoform) by western blot from various cell lines (THP-1) and tissues such as brain. Does not cross-react with PHLPP2.

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Purification: Affinity Purified

Immunogen: human PHLPP1 (amino acids 1192-1205 of the alpha isoform, or amino acids 1704-1717 of the beta isoform)

Isotype: IgG

Application Details

Application Notes: ICC, IHC-P, WB

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 500ul sterile ddH20

Buffer: Lyophilized from 1X TBS.

Storage: 4 °C

Storage Comment: Store at 4°C, stable for one year.

Expiry Date: 12 months

Target Details for PHLPP1

Target: PHLPP1 (PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))

Alternative Name: SCOP / PHLPP

Background: Standard Gene Symbol: PHLPP1, Synonyms: PHLPP1, HSCOP, KIAA0606, PLEKHE1, SCOP, PHLPP

Gene ID: 23239

UniProt: O60346

Pathways: PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway