NDUFA5 antibody (AA 3-116)
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- Target See all NDUFA5 Antibodies
- NDUFA5 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 5, 13kDa (NDUFA5))
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Binding Specificity
- AA 3-116
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This NDUFA5 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Characteristics
- Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13 kDa (NDUFA5), nuclear gene encoding mitochondrial protein
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Human recombinant protein fragment corresponding to amino acids 3-116 of human NDUFA5(NP_004991) produced in HEK293T cell.
- Clone
- 1E8
- Isotype
- IgG1
- Top Product
- Discover our top product NDUFA5 Primary Antibody
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- Application Notes
- WB 1:2000, IF 1:100,
- Comment
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- NDUFA5 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 5, 13kDa (NDUFA5))
- Alternative Name
- NDUFA5 (NDUFA5 Products)
- Synonyms
- NADHUO antibody, B13 antibody, CI-13KD-B antibody, CI-13kB antibody, NUFM antibody, UQOR13 antibody, 2900002J19Rik antibody, NADH:ubiquinone oxidoreductase subunit A5 antibody, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 antibody, Ndufa5 antibody, NDUFA5 antibody
- Background
- The human NDUFA5 gene codes for the B13 subunit of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. The high degree of conservation of NDUFA5 extending to plants and fungi indicates its functional significance in the enzyme complex. The protein localizes to the inner mitochondrial membrane as part of the 7 component-containing, water soluble 'iron-sulfur protein' (IP) fraction of complex I, although its specific role is unknown. It is assumed to undergo post-translational removal of the initiator methionine and N-acetylation of the next amino acid. The predicted secondary structure is primarily alpha helix, but the carboxy-terminal half of the protein has high potential to adopt a coiled-coil form. The amino-terminal part contains a putative beta sheet rich in hydrophobic amino acids that may serve as mitochondrial import signal. Related pseudogenes have also been identified on four other chromosomes.
- Molecular Weight
- 13.3 kDa
- Gene ID
- 4698
- NCBI Accession
- NM_005000
- HGNC
- 4698
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