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TLE2 antibody

TLE2 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2457945
  • Target See all TLE2 Antibodies
    TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))
    Reactivity
    • 22
    • 17
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 32
    • 1
    • 1
    Rabbit
    Clonality
    • 34
    Polyclonal
    Conjugate
    • 17
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLE2 antibody is un-conjugated
    Application
    • 26
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antibody is purified by peptide affinity chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TLE2.
    Top Product
    Discover our top product TLE2 Primary Antibody
  • Application Notes
    TLE2 antibody can be used for detection of TLE2 by ELISA at 1:312500. TLE2 antibody can be used for detection of TLE2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handling Advice
    As with any antibody avoid repeat freeze-thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store TLE2 antibody at -20 °C.
  • Target
    TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))
    Alternative Name
    TLE2 (TLE2 Products)
    Synonyms
    TLE2 antibody, ESG antibody, ESG2 antibody, GRG2 antibody, Grg2 antibody, mKIAA4188 antibody, transducin like enhancer of split 2 antibody, transducin-like enhancer of split 2 antibody, TLE2 antibody, Tle2 antibody
    Background
    TLE2 belongs to the WD repeat Groucho/TLE family. It contains 6 WD repeats. TLE2 is a transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
    Molecular Weight
    80 kDa
    Gene ID
    7089
    NCBI Accession
    NP_003251
    UniProt
    Q04725
    Pathways
    WNT Signaling
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