REG1B antibody

Catalog No. ABIN2458063

Product Details anti-REG1B Antibody

Target: REG1B (Regenerating Islet-Derived 1 beta (REG1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REG1B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human REG1B.

Application Details

Application Notes: REG1B antibody can be used for detection of REG1B by ELISA at 1:62500. REG1B antibody can be used for detection of REG1B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store REG1B antibody at -20 °C.

Target Details for REG1B

Target: REG1B (Regenerating Islet-Derived 1 beta (REG1B))

Alternative Name: REG1B (REG1B Products)

Synonyms: PSPS2 antibody, REGH antibody, REGI-BETA antibody, REGL antibody, regenerating family member 1 beta antibody, REG1B antibody

Background: REG1B might act as an inhibitor of spontaneous calcium carbonate precipitation. REG1B may be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV based on the primary structures of the encoded proteins. This gene encodes a protein secreted by the exocrine pancreas that is highly similar to the REG1A protein. The related REG1A protein is associated with islet cell regeneration and diabetogenesis, and may be involved in pancreatic lithogenesis. Reg family members REG1A, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 16 kDa

Gene ID: 5968

NCBI Accession: NP_006498

UniProt: P48304