PPP1R13B antibody

Catalog No. ABIN2459151

Product Details anti-PPP1R13B Antibody

Target: PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R13B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PPP1R13B.

Application Details

Application Notes: PPP1R13B antibody can be used for detection of PPP1R13B by ELISA at 1:312500. PPP1R13B antibody can be used for detection of PPP1R13B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PPP1R13B antibody at -20 °C.

Target Details for PPP1R13B

Target: PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))

Alternative Name: PPP1R13B (PPP1R13B Products)

Synonyms: ASPP1 antibody, p53BP2-like antibody, p85 antibody, AI449786 antibody, AW545810 antibody, Tp53bp2 antibody, Trp53bp2 antibody, protein phosphatase 1 regulatory subunit 13B antibody, protein phosphatase 1, regulatory subunit 13B antibody, protein phosphatase 1 regulatory subunit 13B L homeolog antibody, protein phosphatase 1, regulatory subunit 13Bb antibody, protein phosphatase 1, regulatory (inhibitor) subunit 13B antibody, PPP1R13B antibody, Ppp1r13b antibody, ppp1r13b.L antibody, ppp1r13bb antibody, ppp1r13b antibody

Background: PPP1R13B is a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.

Molecular Weight: 119 kDa

Gene ID: 23368

NCBI Accession: NP_056131

UniProt: Q96KQ4

Pathways: p53 Signaling