Adenylate Kinase 1 antibody

Catalog No. ABIN2459170

Product Details anti-Adenylate Kinase 1 Antibody

Target: Adenylate Kinase 1 (AK1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adenylate Kinase 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AK1.

Application Details

Application Notes: AK1 antibody can be used for detection of AK1 by ELISA at 1:312500. AK1 antibody can be used for detection of AK1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store AK1 antibody at -20 °C.

Target Details for Adenylate Kinase 1

Target: Adenylate Kinase 1 (AK1)

Alternative Name: AK1 (AK1 Products)

Synonyms: ADK-1 antibody, AK1 antibody, CG17146 antibody, DAK1 antibody, Dak1 antibody, Dmel\\CG17146 antibody, adk1 antibody, bs34e10.y1 antibody, ak5 antibody, ADENYLATE KINASE 1 antibody, MLE2.3 antibody, MLE2_3 antibody, adenylate kinase 1 antibody, Ak-1 antibody, B430205N08Rik antibody, Ak 1 antibody, zgc:91930 antibody, Myokinase antibody, Adenylate kinase 1 antibody, adenylate kinase 1 antibody, Adk1 antibody, ak1 antibody, AK1 antibody, ADK1 antibody, Ak1 antibody

Background: Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 22 kDa

Gene ID: 203

NCBI Accession: NP_000467

UniProt: P00568

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process