CPE antibody

Catalog No. ABIN2460050

Product Details anti-CPE Antibody

Target: CPE (Carboxypeptidase E (CPE))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPE antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CPE.

Application Details

Application Notes: CPE antibody can be used for detection of CPE by ELISA at 1:312500. CPE antibody can be used for detection of CPE by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CPE antibody at -20 °C.

Target Details for CPE

Target: CPE (Carboxypeptidase E (CPE))

Alternative Name: CPE (CPE Products)

Synonyms: CPE antibody, CPH antibody, Cph-1 antibody, Cph1 antibody, R74677 antibody, fat antibody, CARBE antibody, Cph antibody, si:ch211-198g9.2 antibody, zgc:85981 antibody, carboxypeptidase E antibody, carboxypeptidase E L homeolog antibody, CPE antibody, cpe antibody, Cpe antibody, cpe.L antibody

Background: CPE is a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteinsThis gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 52 kDa

Gene ID: 1363

NCBI Accession: NP_001864

UniProt: P16870

Pathways: Peptide Hormone Metabolism, Synaptic Membrane