GATA2 antibody

Catalog No. ABIN2460296

Product Details anti-GATA2 Antibody

Target: GATA2 (GATA Binding Protein 2 (GATA2))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GATA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GATA2.

Application Details

Application Notes: GATA2 antibody can be used for detection of GATA2 by ELISA at 1:1562500. GATA2 antibody can be used for detection of GATA2 by western blot at 1.0-2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GATA2 antibody at -20 °C.

Target Details for GATA2

Target: GATA2 (GATA Binding Protein 2 (GATA2))

Alternative Name: GATA2 (GATA2 Products)

Synonyms: DCML antibody, MONOMAC antibody, NFE1B antibody, Gata-2 antibody, xgata-2 antibody, xgata2 antibody, GATA-2 antibody, NF-E1b antibody, GATA2 antibody, Gata2 antibody, gata2 antibody, zg2 antibody, zgc:91840 antibody, GATA binding protein 2 antibody, GATA binding protein 2 L homeolog antibody, amidase antibody, glutamyl/aspartyl-tRNA(Gln/Asp) amidotransferasesubunit A antibody, hypothetical protein antibody, glutamyl-tRNA(Gln) amidotransferase, subunit GatA (Glu-ADT subunit A) antibody, GATA2 transcription factor antibody, putative gata binding factor antibody, GATA binding protein 2a antibody, GATA binding protein 2b antibody, GATA2 antibody, Gata2 antibody, gata2.L antibody, RR_RS20245 antibody, gatA2 antibody, Smp_018590 antibody, gata2a antibody, gata2b antibody

Background: The GATA family of transcription factors, which contain zinc fingers in their DNA binding domain, have emerged as candidate regulators of gene expression in hematopoietic cells is essential for normal primitive and definitive erythropoiesis and is expressed at high levels in erythroid cells, mast cells, and megakaryocytes. GATA2 is expressed in hematopoietic progenitors, including early erythroid cells, mast cells, and megakaryocytes, and also in nonhematopoietic embryonic stem cells.

Molecular Weight: 50 kDa

Gene ID: 2624

NCBI Accession: NP_116027

UniProt: P23769

Pathways: Stem Cell Maintenance