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SMAD7 antibody

SMAD7 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2460354
  • Target See all SMAD7 Antibodies
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    Reactivity
    • 46
    • 26
    • 24
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 39
    • 7
    Rabbit
    Clonality
    • 40
    • 6
    Polyclonal
    Conjugate
    • 29
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMAD7 antibody is un-conjugated
    Application
    • 26
    • 17
    • 14
    • 14
    • 10
    • 8
    • 8
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antibody is purified by protein A chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMAD7.
    Top Product
    Discover our top product SMAD7 Primary Antibody
  • Application Notes
    SMAD7 antibody can be used for detection of SMAD7 by ELISA at 1:62500. SMAD7 antibody can be used for detection of SMAD7 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handling Advice
    As with any antibody avoid repeat freeze-thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store SMAD7 antibody at -20 °C.
  • Target
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    Alternative Name
    SMAD7 (SMAD7 Products)
    Synonyms
    CRCS3 antibody, MADH7 antibody, MADH8 antibody, Smad7a antibody, Madh7 antibody, Smad10 antibody, madh7 antibody, xsmad7 antibody, wu:fj60c10 antibody, SMAD family member 7 antibody, SMAD family member 7 L homeolog antibody, SMAD7 antibody, Smad7 antibody, smad7.L antibody, smad7 antibody
    Background
    Smad7 acts to functionally inactivate RB and de-repress E2F without blocking the activation of TbetaRI and the nuclear translocation of Smad2/3, allowing TGF-beta1 to exert effects in a cancer cell that is resistant to TGF-beta1-mediated growth inhibition.
    Molecular Weight
    46 kDa
    Gene ID
    4092
    NCBI Accession
    NP_005895
    UniProt
    O15105
    Pathways
    Interferon-gamma Pathway, Cell-Cell Junction Organization
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