CTBP1 antibody

Catalog No. ABIN2460479

Product Details anti-CTBP1 Antibody

Target: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTBP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CTBP1.

Application Details

Application Notes: CTBP1 antibody can be used for detection of CTBP1 by ELISA at 1:62500. CTBP1 antibody can be used for detection of CTBP1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CTBP1 antibody at -20 °C.

Target Details for CTBP1

Target: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Alternative Name: CTBP1 (CTBP1 Products)

Synonyms: BARS antibody, CtBP1-L antibody, CtBP1-S antibody, CtBP3/BARS antibody, D4S115h antibody, D5H4S115 antibody, D5H4S115E antibody, 50-kDaBFA-inducedADP-ribosylatedsubstrate antibody, BARS-50 antibody, Bars antibody, wu:fi43a11 antibody, CtBP antibody, ctbp1-A antibody, xctbp1 antibody, bars antibody, CTBP1 antibody, C-terminal binding protein 1 antibody, C-terminal binding protein 1 L homeolog antibody, CTBP1 antibody, Ctbp1 antibody, ctbp1 antibody, ctbp1.L antibody

Background: CTBP1 binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.

Molecular Weight: 47 kDa, 48 kDa

Gene ID: 1487

NCBI Accession: NP_001012632

UniProt: Q7Z2Q5

Pathways: Retinoic Acid Receptor Signaling Pathway