NR5A2 + LRH1 antibody

Catalog No. ABIN2460492

Product Details anti-NR5A2 + LRH1 Antibody

Target: NR5A2 + LRH1 (NR5A2) (Nuclear Receptor Subfamily 5, Group A, Member 2 (NR5A2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR5A2 + LRH1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR5A2.

Application Details

Application Notes: NR5A2 antibody can be used for detection of NR5A2 by ELISA at 1:1562500. NR5A2 antibody can be used for detection of NR5A2 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NR5A2 antibody at -20 °C.

Target Details for NR5A2 + LRH1

Target: NR5A2 + LRH1 (NR5A2) (Nuclear Receptor Subfamily 5, Group A, Member 2 (NR5A2))

Alternative Name: NR5A2 (NR5A2 Products)

Synonyms: xff1rashort antibody, NR5A2 antibody, b1f antibody, b1f2 antibody, cpf antibody, ff1r antibody, ftf antibody, ftz-f1 antibody, ftz-f1beta antibody, hb1f antibody, hb1f-2 antibody, lrh-1 antibody, lrh1 antibody, xff1ra antibody, B1F antibody, B1F2 antibody, CPF antibody, FTF antibody, FTZ-F1 antibody, FTZ-F1beta antibody, LRH-1 antibody, LRH1 antibody, hB1F-2 antibody, xFF1rB antibody, AU020803 antibody, D1Ertd308e antibody, Ftf antibody, UF2-H3B antibody, Lrh-1 antibody, nuclear receptor subfamily 5 group A member 2 S homeolog antibody, nuclear receptor subfamily 5 group A member 2 antibody, nuclear receptor subfamily 5 group A member 2 L homeolog antibody, nuclear receptor subfamily 5, group A, member 2 antibody, nr5a2.S antibody, NR5A2 antibody, nr5a2 antibody, nr5a2.L antibody, Nr5a2 antibody

Background: NR5A2 binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. It may be responsable for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. It is a key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. It may also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.

Molecular Weight: 36 kDa

Gene ID: 2494

UniProt: O60587

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway