NR4A2 antibody
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- Target See all NR4A2 Antibodies
- NR4A2 (Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2))
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Reactivity
- Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Drosophila melanogaster
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NR4A2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR4A2.
- Top Product
- Discover our top product NR4A2 Primary Antibody
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- Application Notes
- NR4A2 antibody can be used for detection of NR4A2 by ELISA at 1:62500. NR4A2 antibody can be used for detection of NR4A2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store NR4A2 antibody at -20 °C.
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- Target
- NR4A2 (Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2))
- Alternative Name
- NR4A2 (NR4A2 Products)
- Synonyms
- nr41/42/43 antibody, Nr4a2 antibody, nurr1 antibody, not antibody, rnr1 antibody, hzf-3 antibody, tinur antibody, NGFI-B antibody, HZF-3 antibody, NOT antibody, NURR1 antibody, RNR1 antibody, TINUR antibody, Nurr1 antibody, RNR-1 antibody, TINOR antibody, ngf1b antibody, nr4a2 antibody, zgc:92696 antibody, nuclear receptor subfamily 4 group A member 2 antibody, nuclear receptor antibody, nuclear receptor subfamily 4, group A, member 2 antibody, nuclear receptor subfamily 4, group A, member 2b antibody, NR4A2 antibody, nr41/42/43 antibody, nr4a2 antibody, Nr4a2 antibody, nr4a2b antibody
- Background
- NR4A2 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. The protein may act as a transcription factor. Mutations in NR4A2 gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of NR4A2 gene may be associated with rheumatoid arthritis.This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Four transcript variants encoding four distinct isoforms have been identified for this gene. Additional alternate splice variants may exist, but their full length nature has not been determined.
- Molecular Weight
- 66 kDa, 64 kDa, 68 kDa, 64 kDa, 65 kDa, 60 kDa, 68 kDa, 70 kDa
- Gene ID
- 4929
- NCBI Accession
- NP_006177
- UniProt
- P43354
- Pathways
- Nuclear Receptor Transcription Pathway, Dopaminergic Neurogenesis, Steroid Hormone Mediated Signaling Pathway
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