TBX3 antibody

Catalog No. ABIN2460723

Product Details anti-TBX3 Antibody

Target: TBX3 (T-Box 3 (TBX3))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBX3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TBX3.

Application Details

Application Notes: TBX3 antibody can be used for detection of TBX3 by ELISA at 1:62500. TBX3 antibody can be used for detection of TBX3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TBX3 antibody at -20 °C.

Target Details for TBX3

Target: TBX3 (T-Box 3 (TBX3))

Alternative Name: TBX3 (TBX3 Products)

Synonyms: xtbx3 antibody, ums antibody, xhl antibody, tbx3-iso antibody, TBX3 antibody, TBX3-ISO antibody, UMS antibody, XHL antibody, D5Ertd189e antibody, T-box 3 antibody, T-box 3 S homeolog antibody, TBX3 antibody, tbx3.S antibody, tbx3 antibody, Tbx3 antibody

Background: TBX3 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms, however, the full length nature of one variant has not been determined.

Molecular Weight: 66 kDa, 77 kDa, 79 kDa

Gene ID: 6926

Pathways: Hormone Transport, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development