RUNX1T1 antibody
-
- Target See all RUNX1T1 Antibodies
- RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
-
Reactivity
- Human, Mouse, Rat, Dog, Zebrafish (Danio rerio)
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This RUNX1T1 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by protein A chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RUNX1T1.
- Top Product
- Discover our top product RUNX1T1 Primary Antibody
-
-
- Application Notes
- RUNX1T1 antibody can be used for detection of RUNX1T1 by ELISA at 1:312500. RUNX1T1 antibody can be used for detection of RUNX1T1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store RUNX1T1 antibody at -20 °C.
-
- Target
- RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
- Alternative Name
- RUNX1T1 (RUNX1T1 Products)
- Synonyms
- MTG8 antibody, si:ch211-232j17.1 antibody, wu:fi14b07 antibody, zgc:154044 antibody, AML1T1 antibody, CBFA2T1 antibody, CDR antibody, ETO antibody, ZMYND2 antibody, Cbfa2t1h antibody, Cbfa2t1 antibody, runt-related transcription factor 1; translocated to, 1 (cyclin D-related) antibody, RUNX1 translocation partner 1 L homeolog antibody, RUNX1 translocation partner 1 antibody, runx1t1 antibody, runx1t1.L antibody, RUNX1T1 antibody, Runx1t1 antibody
- Background
- RUNX1T1 is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t (8,21) (q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation.
- Molecular Weight
- 62 kDa
- Gene ID
- 862
- NCBI Accession
- NP_783554
- UniProt
- Q06455
-