MCM5 antibody

Catalog No. ABIN2461397

Product Details anti-MCM5 Antibody

Target: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCM5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MCM5.

Application Details

Application Notes: MCM5 antibody can be used for detection of MCM5 by ELISA at 1:62500. MCM5 antibody can be used for detection of MCM5 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MCM5 antibody at -20 °C.

Target Details for MCM5

Target: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Alternative Name: MCM5 (MCM5 Products)

Synonyms: 23.m06024 antibody, cdc46 antibody, xmcm5 antibody, CDC46 antibody, P1-CDC46 antibody, Afu5g02520 antibody, NCU01171.1 antibody, AA617332 antibody, AI324988 antibody, AL033333 antibody, Cdc46 antibody, Mcmd5 antibody, mCD46 antibody, mCDC46 antibody, mcm5 antibody, wu:fb34a06 antibody, CG4082 antibody, DmCDC46 antibody, DmCDC465 antibody, DmMCM5 antibody, DmMcm5 antibody, DmeMCM5 antibody, Dmel\\CG4082 antibody, MCM5 antibody, McM5 antibody, PCR4 antibody, DNA replication licensing factor MCM5 antibody, minichromosome maintenance complex component 5 S homeolog antibody, minichromosome maintenance complex component 5 antibody, DNA replication licensing factor Mcm5 antibody, DNA replication licensing factor mcm5 antibody, MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) antibody, minichromosome maintenance complex component 5 L homeolog antibody, Minichromosome maintenance 5 antibody, DNA replication licensing factor mcm-5 antibody, BBOV_IV010040 antibody, mcm5.S antibody, MCM5 antibody, AFUA_5G02520 antibody, NCU01171 antibody, PVX_084615 antibody, LOC5576119 antibody, CpipJ_CPIJ008678 antibody, Bm1_24480 antibody, CMU_022890 antibody, Mcm5 antibody, mcm5 antibody, TP01_0722 antibody, mcm5.L antibody, mcm-5 antibody

Background: The protein encoded by MCM5 is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.

Molecular Weight: 82 kDa

Gene ID: 4174

NCBI Accession: NP_006730

UniProt: P33992

Pathways: DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA