G3BP1 antibody

Catalog No. ABIN2461581

Product Details anti-G3BP1 Antibody

Target: G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))

Reactivity: Human, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This G3BP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human G3BP.

Application Details

Application Notes: G3BP antibody can be used for detection of G3BP by ELISA at 1:312500. G3BP antibody can be used for detection of G3BP by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store G3BP antibody at -20 °C.

Target Details for G3BP1

Target: G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))

Alternative Name: G3BP (G3BP1 Products)

Synonyms: G3BP antibody, HDH-VIII antibody, fj17h05 antibody, zgc:56034 antibody, wu:fj17h05 antibody, g3bp antibody, MGC53271 antibody, G3BP1 antibody, G3bp antibody, RGD1310666 antibody, AI849976 antibody, B430204O07 antibody, C87777 antibody, mKIAA4115 antibody, G3BP stress granule assembly factor 1 antibody, GTPase activating protein (SH3 domain) binding protein 1 antibody, GTPase activating protein (SH3 domain) binding protein 1 L homeolog antibody, Ras-GTPase-activating protein SH3-domain-binding protein antibody, G3BP1 antibody, g3bp1 antibody, g3bp1.L antibody, LOC100304885 antibody, G3bp1 antibody

Background: G3BP is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Molecular Weight: 51 kDa, 52 kDa

Gene ID: 10146

NCBI Accession: NP_005745

UniProt: Q13283

Pathways: SARS-CoV-2 Protein Interactome