GSC2 antibody
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- Target See all GSC2 Antibodies
- GSC2 (Goosecoid Homeobox 2 (GSC2))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GSC2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- Antibody is purified by protein A chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GSCL.
- Top Product
- Discover our top product GSC2 Primary Antibody
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- Application Notes
- GSCL antibody can be used for detection of GSCL by ELISA at 1:1562500. GSCL antibody can be used for detection of GSCL by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store GSCL antibody at -20 °C.
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- Target
- GSC2 (Goosecoid Homeobox 2 (GSC2))
- Alternative Name
- GSCL (GSC2 Products)
- Synonyms
- Gscl antibody, GSCL antibody, 4930568H22Rik antibody, GSC-2 antibody, goosecoid homeobox 2 antibody, goosecoid homebox 2 antibody, Gsc2 antibody, GSC2 antibody
- Background
- Goosecoidlike (GSCL) resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology.Goosecoidlike (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology. The gene is expressed in a limited number of adult tissues, as well as in early human development.
- Molecular Weight
- 22 kDa
- Gene ID
- 2928
- NCBI Accession
- NP_005306
- UniProt
- O15499
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