Cyclin B3 antibody

Catalog No. ABIN2461962

Product Details anti-Cyclin B3 Antibody

Target: Cyclin B3 (CCNB3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin B3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CCNB3.

Application Details

Application Notes: CCNB3 antibody can be used for detection of CCNB3 by ELISA at 1:312500. CCNB3 antibody can be used for detection of CCNB3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CCNB3 antibody at -20 °C.

Target Details for Cyclin B3

Target: Cyclin B3 (CCNB3)

Alternative Name: CCNB3 (CCNB3 Products)

Synonyms: CG5814 antibody, Cyc B3 antibody, Dmel\\CG5814 antibody, anon-WO0118547.414 antibody, cycB3 antibody, l(3)L6540 antibody, ccnb3-a antibody, zgc:153369 antibody, MGC154490 antibody, NV16541 antibody, CCNB3 antibody, CYCB3 antibody, RGD1564367 antibody, Cyclin B3 antibody, cyclin B3 S homeolog antibody, cyclin B3 antibody, cyclin B3 L homeolog antibody, G2/mitotic-specific cyclin-B3 antibody, CycB3 antibody, ccnb3.S antibody, ccnb3 antibody, ccnb3.L antibody, LOC5572162 antibody, LOC100122822 antibody, CCNB3 antibody, LOC100394742 antibody, Ccnb3 antibody

Background: CCNB3 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event.This cyclin may associate with CDC2 and CDK2 kinases, and be required for proper spindle reorganization and restoration of the interphase nucleus.The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chick and Drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and be required for proper spindle reorganization and restoration of the interphase nucleus. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 12 kDa, 158 kDa, 33 kDa

Gene ID: 85417

NCBI Accession: NP_391991

UniProt: Q8WWL7

Pathways: Cell Division Cycle, Chromatin Binding