CPSF2 antibody

Catalog No. ABIN2462270

Product Details anti-CPSF2 Antibody

Target: CPSF2 (Cleavage and Polyadenylation Specific Factor 2, 100kDa (CPSF2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPSF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CPSF2.

Application Details

Application Notes: CPSF2 antibody can be used for detection of CPSF2 by ELISA at 1:62500. CPSF2 antibody can be used for detection of CPSF2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CPSF2 antibody at -20 °C.

Target Details for CPSF2

Target: CPSF2 (Cleavage and Polyadenylation Specific Factor 2, 100kDa (CPSF2))

Alternative Name: CPSF2 (CPSF2 Products)

Synonyms: CPSF100 antibody, 100kDa antibody, 2610024B04Rik antibody, AI662483 antibody, Cpsf antibody, MCPSF antibody, mKIAA1367 antibody, zgc:92484 antibody, cpsf2-A antibody, cleavage and polyadenylation specific factor 2 antibody, cleavage and polyadenylation specific factor 2 S homeolog antibody, cleavage and polyadenylation specificity factor subunit 2 antibody, CPSF2 antibody, Cpsf2 antibody, cpsf2 antibody, PAAG_07931 antibody, cpsf2.S antibody, LOC582050 antibody, LOC100157277 antibody, LOC100179344 antibody

Background: CPSF2 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition. It belongs to the metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, CPSF2/YSH1 subfamily.

Molecular Weight: 88 kDa

Gene ID: 53981

NCBI Accession: NP_059133

UniProt: Q9P2I0