C21orf33 antibody can be used for detection of C21orf33 by ELISA at 1:1562500. C21orf33 antibody can be used for detection of C21orf33 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Concentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Handling Advice
As with any antibody avoid repeat freeze-thaw cycles.
Storage
4 °C/-20 °C
Storage Comment
For short periods of storage (days) store at 4 °C. For longer periods of storage, store C21orf33 antibody at -20 °C.
Target
C21orf33
(Chromosome 21 Open Reading Frame 33 (C21orf33))
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Background
C21orf33 inhibits both estrogen- and heregulin-beta1-stimulated growth of breast cancer cells, and further suggests that growth inhibition induced in these cells by all-trans retinoic acid occurs via HES-1-mediated downregulation of E2F-1 expression. C21orf33 may also be a candidate protein involved in the pathogenesis of the brain deficit in DS.