GPAA1 antibody

Catalog No. ABIN2462976

Product Details anti-GPAA1 Antibody

Target: GPAA1 (GPI Anchor Attachment Protein 1 (GPAA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPAA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GPAA1.

Application Details

Application Notes: GPAA1 antibody can be used for detection of GPAA1 by ELISA at 1:62500. GPAA1 antibody can be used for detection of GPAA1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GPAA1 antibody at -20 °C.

Target Details for GPAA1

Target: GPAA1 (GPI Anchor Attachment Protein 1 (GPAA1))

Alternative Name: GPAA1 (GPAA1 Products)

Synonyms: GAA1 antibody, hGAA1 antibody, C80044 antibody, mGAA1 antibody, glycosylphosphatidylinositol anchor attachment 1 antibody, GPI anchor attachment protein 1 antibody, GPAA1 antibody, Gpaa1 antibody

Background: Posttranslational glycosylphosphatidylinositol (GPI) anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane. GPAA1 presumably functions in GPI anchoring at the GPI transfer step. The anchor attachment protein 1 contains an N-terminal signal sequence, 1 cAMP- and cGMP-dependent protein kinase phosphorylation site, 1 leucine zipper pattern, 2 potential N-glycosylation sites, and 8 putative transmembrane domains.Posttranslational glycosylphosphatidylinositol (GPI) anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane. The protein encoded by this gene presumably functions in GPI anchoring at the GPI transfer step. The mRNA transcript is ubiquitously expressed in both fetal and adult tissues. The anchor attachment protein 1 contains an N-terminal signal sequence, 1 cAMP- and cGMP-dependent protein kinase phosphorylation site, 1 leucine zipper pattern, 2 potential N-glycosylation sites, and 8 putative transmembrane domains.

Molecular Weight: 67 kDa

Gene ID: 8733

NCBI Accession: NP_003792

UniProt: O43292

Pathways: Inositol Metabolic Process, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome