CDR2 antibody

Catalog No. ABIN2463409

Product Details anti-CDR2 Antibody

Target: CDR2 (Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDR2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDR2.

Application Details

Application Notes: CDR2 antibody can be used for detection of CDR2 by ELISA at 1:312500. CDR2 antibody can be used for detection of CDR2 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CDR2 antibody at -20 °C.

Target Details for CDR2

Target: CDR2 (Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2))

Alternative Name: CDR2 (CDR2 Products)

Synonyms: CDR62 antibody, Yo antibody, cdr2 antibody, MGC69206 antibody, CDR2 antibody, AA617262 antibody, RGD1310578 antibody, cerebellar degeneration related protein 2 antibody, cerebellar degeneration related protein 2 L homeolog antibody, cerebellar degeneration-related 2 antibody, cerebellar degeneration-related protein 2 antibody, cerebellar degeneration related protein 2 like antibody, CDR2 antibody, cdr2 antibody, cdr2.L antibody, Cdr2 antibody, CDR2L antibody, LOC101060399 antibody

Background: Cdr2 normally sequesters c-Myc in the neuronal cytoplasm, thereby down-regulating c-Myc activity, and suggest a mechanism whereby inhibition of cdr2 function by autoantibodies in PCD may contribute to Purkinje neuronal.

Molecular Weight: 52 kDa

Gene ID: 1039

NCBI Accession: NP_001793

UniProt: Q01850