IRF8 antibody

Catalog No. ABIN2463831

Product Details anti-IRF8 Antibody

Target: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IRF8.

Application Details

Application Notes: IRF8 antibody can be used for detection of IRF8 by ELISA at 1:62500. IRF8 antibody can be used for detection of IRF8 by western blot at 0.5-2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store IRF8 antibody at -20 °C.

Target Details for IRF8

Target: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Alternative Name: IRF8 (IRF8 Products)

Synonyms: zgc:92252 antibody, IRF8 antibody, MGC140338 antibody, DKFZp469B0320 antibody, H-ICSBP antibody, ICSBP antibody, ICSBP1 antibody, IRF-8 antibody, icsbp1 antibody, AI893568 antibody, Icsbp1 antibody, Myls antibody, interferon regulatory factor 8 antibody, interferon regulatory factor 8 L homeolog antibody, irf8 antibody, IRF8 antibody, irf8.L antibody, Irf8 antibody

Background: Interferon regulatory factor 8 (IRF8, interferon consensus sequence-binding protein, Ion ChannelSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-. and IFN-.. IRF family proteins also control expression of IFN-. and IFN-.-regulated genes that are induced by viral infection.

Molecular Weight: 48 kDa

Gene ID: 3394

NCBI Accession: NP_002154

UniProt: Q02556

Pathways: Cellular Response to Molecule of Bacterial Origin