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Aurora Kinase B antibody (truncated)
AURKB
Reactivity: Human
WB, ELISA
Host: Mouse
Monoclonal
13E8D3
unconjugated
Product Details anti-Aurora Kinase B Antibody
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Target
See all Aurora Kinase B (AURKB) Antibodies
Aurora Kinase B (AURKB)
Binding Specificity
All epitopes for Aurora Kinase B antibodies
truncated
Reactivity
All reactivities for Aurora Kinase B antibodies
Human
Host
All hosts for Aurora Kinase B antibodies
Mouse
Clonality
All clonalities for Aurora Kinase B antibodies
Monoclonal
Conjugate
All conjugates for Aurora Kinase B antibodies
This Aurora Kinase B antibody is un-conjugated
Application
All applications for Aurora Kinase B antibodies
Western Blotting (WB), ELISA
Immunogen
Ni-NTA purified truncated recombinant AURKB expressed in E. Coli strain BL21 (DE3).
Clone
13E8D3
Isotype
IgG1
Top Product
Discover our top product AURKB Primary Antibody
Alternatives
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Application Details
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Application Notes
Western Blot:1:500 - 1:2,000 ELISA:Propose dilution 1:10,000. Determining optimal working dilutions by titration test.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Ascitic fluid containing 0.03 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage
-20 °C
Storage Comment
AURKB monoclonal antibody can be stored at -20 °C, stable for one year.
Target Details for Aurora Kinase B
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Target
Aurora Kinase B (AURKB)
Alternative Name
AURKB (AURKB Products )
Synonyms
AIK2 antibody, AIM-1 antibody, AIM1 antibody, ARK2 antibody, AurB antibody, IPL1 antibody, PPP1R48 antibody, STK12 antibody, STK5 antibody, aurkb-sv1 antibody, aurkb-sv2 antibody, AIRK2 antibody, AL022959 antibody, Aik2 antibody, Aim1 antibody, Ark2 antibody, STK-1 antibody, Stk12 antibody, Stk5 antibody, Aur B antibody, Aurora B antibody, Aurora-B antibody, CG6620 antibody, DmAIRK2 antibody, DmAurB antibody, DmAuroraB antibody, Dmel\\CG6620 antibody, IAL antibody, IAL1 antibody, Ial antibody, aurB antibody, aurora B antibody, ARK-2 antibody, XAIRK2 antibody, aik2 antibody, aim-1 antibody, aim1 antibody, airk2 antibody, ark2 antibody, ipl1 antibody, stk12 antibody, stk5 antibody, CHUNP6896 antibody, fa09g06 antibody, stka antibody, wu:fa09g06 antibody, aurkb antibody, AIRK2-B antibody, XAIRK2-B antibody, aurkb-a antibody, aurkb-b antibody, xAurora-B-B antibody, aurora kinase B antibody, aurora B antibody, aurora kinase B S homeolog antibody, AURKB antibody, Aurkb antibody, aurB antibody, aurkb antibody, aurkb.S antibody
Background
AURKB (aurora kinase B, AIK2 or aurora-B), with 344-amino acid protein(about 39 kDa),localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers. AURKB is a mitotic protein kinase, which phosphorylates histone H3 and regulates Chromosomal segregation during mitosis and meiosis.It may regulates several stages of mitosis such as centrosome separation, chromosome segregation and cytokinesis.Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. ARK-2 transcripts arepresent at high levels in human thymus and fetal liver.ARK-2 protein levels are maximal during both S and G2/M phases
Gene ID
9212
UniProt
Q96GD4
Pathways
TCR Signaling , Cell Division Cycle , Maintenance of Protein Location , Hepatitis C , Toll-Like Receptors Cascades
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