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BLK antibody (truncated)

BLK Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal 9D10B7 unconjugated

Catalog No. ABIN2464017

Datasheet as PDF

Target See all BLK Antibodies

BLK (B Lymphoid Tyrosine Kinase (BLK))
Binding Specificity
15

13

9

7

4

3

3

2

2

2

1

1

1

1

1

1

1
truncated
Reactivity
66

23

14

2

1

1

1

1

1

1

1
Human
Host
53

10

1
Mouse
Compatible Secondaries
Clonality
55

11
Monoclonal
Conjugate
35

4

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1
This BLK antibody is un-conjugated
Application
52

37

28

13

13

8

4

3

2

2

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen

Ni-NTA purified truncated recombinant BLK expressed in E. Coli strain BL21 (DE3).

Clone

9D10B7

Isotype

IgG1

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BLK Reactivity: Human WB, ELISA Host: Mouse Monoclonal 7A12 unconjugated

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BLK Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB03107 unconjugated

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BLK Reactivity: Human WB, ELISA, ICC, FACS Host: Mouse Monoclonal 1-00E-06 unconjugated

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BLK Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3E5-3A8 unconjugated

anti-B Lymphoid Tyrosine Kinase (BLK) antibody
BLK Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal 9D10B7 unconjugated

anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-280) antibody
BLK Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-505) antibody
BLK Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated

anti-B Lymphoid Tyrosine Kinase (BLK) antibody
BLK Reactivity: Human ELISA, IHC Host: Mouse Monoclonal 9D10D1 unconjugated

anti-B Lymphoid Tyrosine Kinase (BLK) (N-Term) antibody
BLK Reactivity: Human, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated

Application Notes

Western Blot:1:500 - 1:2,000
IHC(P):1:500 - 1:2,000
IHC(F):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Restrictions

For Research Use only
Format

Liquid

Handling Advice

As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage

-20 °C

Storage Comment

BLK monoclonal antibody can be stored at -20 °C, stable for one year.
Target

BLK (B Lymphoid Tyrosine Kinase (BLK))

Alternative Name

BLK (BLK Products)

Synonyms

bltk antibody, si:dkey-33i22.2 antibody, zgc:136231 antibody, MODY11 antibody, BLK proto-oncogene, Src family tyrosine kinase antibody, B lymphoid kinase antibody, blk antibody, BLK antibody, Blk antibody

Background

BLK ( B lymphoid tyrosine kinase), with 505-amino acid protein (about 56 kDa), belongs to the Src non-receptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking. Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.

Gene ID

640

UniProt

P51451

Pathways

Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling