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GSK3 alpha antibody (truncated)
GSK3a
Reactivity: Human
WB, IHC, ELISA
Host: Mouse
Monoclonal
6G2F1-6G2F2
unconjugated
Product Details anti-GSK3 alpha Antibody
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Target
See all GSK3 alpha (GSK3a) Antibodies
GSK3 alpha (GSK3a)
(Glycogen Synthase Kinase 3 alpha (GSK3a))
Binding Specificity
All epitopes for GSK3 alpha antibodies
truncated
Reactivity
All reactivities for GSK3 alpha antibodies
Human
Host
All hosts for GSK3 alpha antibodies
Mouse
Clonality
All clonalities for GSK3 alpha antibodies
Monoclonal
Conjugate
All conjugates for GSK3 alpha antibodies
This GSK3 alpha antibody is un-conjugated
Application
All applications for GSK3 alpha antibodies
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
Immunogen
Ni-NTA purified truncated recombinant GSK3 alpha expressed in E. Coli strain BL21 (DE3).
Clone
6G2F1-6G2F2
Top Product
Discover our top product GSK3a Primary Antibody
Alternatives
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Application Details
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Application Notes
Western Blot:1:500 - 1:2,000 IHC(P):1:500 - 1:2,000 IHC(F):1:500 - 1:2,000 ELISA:Propose dilution 1:10,000. Determining optimal working dilutions by titration test.
Restrictions
For Research Use only
Handling
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Format
Liquid
Handling Advice
As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage
-20 °C
Storage Comment
GSK3 alpha monoclonal antibody can be stored at -20 °C, stable for one year.
Target Details for GSK3 alpha
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Target
GSK3 alpha (GSK3a)
(Glycogen Synthase Kinase 3 alpha (GSK3a))
Alternative Name
GSK3alpha (GSK3a Products )
Synonyms
2700086H06Rik antibody, GSK3A antibody, GSK-3[a] antibody, GSK-3[b] antibody, GSK3 antibody, gsk3a antibody, xgsk3 antibody, glycogen synthase kinase 3 alpha antibody, glycogen synthase kinase 3 alpha b antibody, glycogen synthase kinase 3 alpha S homeolog antibody, GSK3A antibody, Gsk3a antibody, gsk3a antibody, gsk3ab antibody, gsk3a.S antibody, Bm1_31380 antibody
Background
GSK3 alpha (Glycogen synthase kinase 3 alpha), with 483-amino acid protein (about 53 kDa), belongs to the Ser/Thr family of protein kinases, Cdc2/cdkx subfamily,GSK3 subsubfamily, which also includes GSK3 beta.GSK3 is a multifunctional serine/threonine kinase that is usually inactivated by serine phosphorylation in response to extracellular cues. GSK3 is a key regulator of numerous signalling pathways, including cellular responses to Wnt, receptor tyrosine kinases and G-protein-coupled receptors and is involved in a wide range of cellular processes, ranging from glycogen metabolism to cell cycle regulation and proliferation.GSK3 alpha is implicated in the control of several regulatory proteins including glycogen synthase and transcription factors.
Gene ID
2931
UniProt
P49840
Pathways
PI3K-Akt Signaling , WNT Signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , cAMP Metabolic Process , Cellular Glucan Metabolic Process , Regulation of Muscle Cell Differentiation , Regulation of G-Protein Coupled Receptor Protein Signaling , ER-Nucleus Signaling , Regulation of Carbohydrate Metabolic Process , BCR Signaling , Warburg Effect
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