IL-6 antibody
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- Target See all IL-6 (IL6) Antibodies
- IL-6 (IL6) (Interleukin 6 (IL6))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This IL-6 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Immunogen
- Ni-NTA purified recombinant human IL-6 expressed in E. Coli strain BL21 (DE3).
- Clone
- 6D9A1
- Isotype
- IgG1
- Top Product
- Discover our top product IL6 Primary Antibody
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- Application Notes
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Western Blot:1:200 - 1:1,000
ELISA:Propose dilution 1:10,000
Determining optimal working dilutions by titration test.
- Restrictions
- For Research Use only
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- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Storage
- -20 °C
- Storage Comment
- IL-6 monoclonal antibody can be stored at -20 °C, stable for one year.
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- Target
- IL-6 (IL6) (Interleukin 6 (IL6))
- Alternative Name
- IL-6 (IL6 Products)
- Synonyms
- BSF2 antibody, HGF antibody, HSF antibody, IFNB2 antibody, IL-6 antibody, Il-6 antibody, ILg6 antibody, Ifnb2 antibody, il6 antibody, CHIL-6 antibody, interleukin 6 antibody, interleukin-6 antibody, IL6 antibody, Il6 antibody, il-6 antibody, IL-6 antibody
- Background
- Interleukine 6 (IL-6) is a cytokine produced primarily by stimulated monocytes, fibroblasts and epithelial cells. It has a wide variety of biological functions through activating a cellsurface signaling assembly composed of IL6, IL6RA, and the shared signaling receptor gp130. The cytokine plays an essential role in the final differentiation of b-cells into Igsecreting cells, and induces myeloma, plasmacytoma growth, nerve cells differentiations. In addition, IL-6 is an important regulator of acute phase reaction.
- Gene ID
- 3569
- NCBI Accession
- NP_000591
- UniProt
- P05231
- Pathways
- TLR Signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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