IL-10 antibody
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- Target See all IL-10 (IL10) Antibodies
- IL-10 (IL10) (Interleukin 10 (IL10))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This IL-10 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by protein A affinity chromatography.
- Immunogen
- Ni-NTA purified recombinant human IL-10 expressed in E. Coli strain BL21 (DE3).
- Clone
- 3C12C12
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product IL10 Primary Antibody
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- Application Notes
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Western Blot:1:500 - 1,000
ELISA:Determining optimal working dilutions by titration test.
- Restrictions
- For Research Use only
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- Buffer
- Purified antibody in PBS containing 0.03 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Storage
- -20 °C
- Storage Comment
- to IL-10 monoclonal antibody can be stored at -20 °C, stable for one year.
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- Target
- IL-10 (IL10) (Interleukin 10 (IL10))
- Alternative Name
- IL-10 (IL10 Products)
- Synonyms
- CSIF antibody, GVHDS antibody, IL-10 antibody, IL10A antibody, TGIF antibody, Il-10 antibody, IL10X antibody, interleukin 10 antibody, IL10 antibody, Il10 antibody
- Background
- Interleukine 10 (IL-10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down- regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
- Gene ID
- 3586
- UniProt
- P22301
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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