p53 antibody (AA 181-190)

Catalog No. ABIN2476010

There are 2+ publications for this product available. The Mouse Monoclonal anti-p53 antibody is suitable to detect p53 in samples from Human. It has been validated for WB, IHC (p), IP and IHC (fro).

Quick Overview for p53 antibody (AA 181-190) (ABIN2476010)

Target: p53 (TP53) (Tumor Protein P53 (TP53))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This p53 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: DO-11

Product Details anti-p53 Antibody

Binding Specificity: AA 181-190

Characteristics: Purified IgG

Purification: Purified

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-p53 antibody (ABIN2476010)

Palecek, Brázdová, Brázda, Palecek, Billová, Subramaniam, Jovin: "Binding of p53 and its core domain to supercoiled DNA." in: European journal of biochemistry / FEBS, Vol. 268, Issue 3, pp. 573-81, (2001) (PubMed).

Coomber, Ward: "Isolation of human antibodies against the central DNA binding domain of p53 from an individual with colorectal cancer using antibody phage display." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 7, Issue 9, pp. 2802-8, (2001) (PubMed).

Target Details for p53

Target: p53 (TP53) (Tumor Protein P53 (TP53))

Alternative Name: p53

Gene ID: 7157

UniProt: P04637

Pathways: p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect