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p53 antibody (AA 181-190)

Name: p53 antibody (AA 181-190)
SKU: ABIN2476010
Price: 487 USD
Availability: InStock

TP53 Reactivity: Human WB, IHC (p), IP, IHC (fro) Host: Mouse Monoclonal DO-11 unconjugated

(2 references)

Catalog No. ABIN2476010

Datasheet as PDF

Target See all p53 (TP53) Antibodies

p53 (TP53) (Tumor Protein P53 (TP53))
Binding Specificity
41

39

37

31

29

28

26

26

24

22

21

19

19

18

18

18

16

15

13

12

9

8

8

8

7

7

6

6

6

6

6

6

6

5

5

4

4

4

4

4

4

4

3

3

3

3

3

3

3

3
AA 181-190
Reactivity
818

258

211

101

46

33

30

18

10

10

9

6

6

3

3

3

2

2

2

2

2

1

1
Human
Host
619

217

5

2

2
Mouse
Compatible Secondaries
Clonality
569

275

1
Monoclonal
Conjugate
460

39

32

20

18

14

14

14

14

14

14

14

14

14

12

11

11

11

11

11

11

11

11

5

5

5

5

5

5

2

2

2

2

2

2

2

1

1

1

1

1

1
This p53 antibody is un-conjugated
Application
649

296

243

196

193

143

129

122

112

61

54

32

20

17

17

12

10

9

8

6

4

3

3

2

2

2

1

1

1

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Characteristics

Purified IgG

Purification

Purified

Clone

DO-11

Isotype

IgG1

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anti-Tumor Protein P53 (TP53) (pSer33) antibody
TP53 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Concentration

1.0 mg/mL
Palecek, Brázdová, Brázda, Palecek, Billová, Subramaniam, Jovin: "Binding of p53 and its core domain to supercoiled DNA." in: European journal of biochemistry / FEBS, Vol. 268, Issue 3, pp. 573-81, (2001) (PubMed).

Coomber, Ward: "Isolation of human antibodies against the central DNA binding domain of p53 from an individual with colorectal cancer using antibody phage display." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 7, Issue 9, pp. 2802-8, (2001) (PubMed).
Target

p53 (TP53) (Tumor Protein P53 (TP53))

Alternative Name

p53 (TP53 Products)

Gene ID

7157

UniProt

P04637

Pathways

p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect