PTH1R antibody (N-Term)

Catalog No. ABIN2498780

Product Details anti-PTH1R Antibody

Target: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Cow, Pig, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTH1R antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ARIAPGLALL LCCPVLSSAY ALVDADDVMT KEEQIFLLHR AQAQCEKRLK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PTH1R. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human PTH1R

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PTH1R

Target: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Alternative Name: PTH1R (PTH1R Products)

Synonyms: PFE antibody, PTHR antibody, PTHR1 antibody, PPR antibody, Pthr antibody, Pthr1 antibody, pthr1 antibody, zPTH1R antibody, PTHrel antibody, PTH1 antibody, PTH antibody, parathyroid hormone 1 receptor antibody, parathyroid hormone 1 receptor a antibody, PTH1R antibody, Pth1r antibody, pth1ra antibody

Background: The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: PFE, PTHR, PTHR1
Protein Size: 333

Molecular Weight: 36 kDa

Gene ID: 5745

NCBI Accession: NM_000316, NP_000307

UniProt: Q03431

Pathways: Regulation of Carbohydrate Metabolic Process