SP1 antibody (Middle Region)
SP1
Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Rabbit, Guinea Pig
WB
Host: Rabbit
Polyclonal
unconjugated
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Target
See all SP1 Antibodies
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SP1
(Sp1 Transcription Factor (SP1))
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Binding Specificity
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Middle Region
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Reactivity
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Human, Mouse, Rat, Cow, Dog, Goat, Rabbit, Guinea Pig
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Host
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Rabbit
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Clonality
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Polyclonal
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Conjugate
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This SP1 antibody is un-conjugated
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Application
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Western Blotting (WB)
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Sequence
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ETLQNLQLQA VPNSGPIIIR TPTVGPNGQV SWQTLQ
LQNLQVQNPQ AQT
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Predicted Reactivity
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Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Characteristics
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This is a rabbit polyclonal antibody against SP1. It was validated on Western Blot.
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Purification
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Affinity Purified
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Immunogen
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The immunogen is a synthetic peptide directed towards the middle region of Human SP1
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Top Product
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Discover our top product SP1 Primary Antibody
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Application Notes
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Optimal working dilution should be determined by the investigator.
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Restrictions
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For Research Use only
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Format
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Liquid
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Concentration
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1 mg/mL
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Buffer
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Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
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Sodium azide
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Precaution of Use
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This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
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Avoid repeat freeze-thaw cycles.
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Storage
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-20 °C
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Storage Comment
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For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Target
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SP1
(Sp1 Transcription Factor (SP1))
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Alternative Name
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SP1 (SP1 Products)
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Synonyms
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fc18h09 antibody, zgc:85950 antibody, wu:fc18h09 antibody, SP1 antibody, 1110003E12Rik antibody, AA450830 antibody, AI845540 antibody, Sp1-1 antibody, sp1 transcription factor antibody, Sp1 transcription factor antibody, Sp1 transcription factor L homeolog antibody, trans-acting transcription factor 1 antibody, sp1 antibody, SP1 antibody, Sp1 antibody, sp1.L antibody
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Background
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SP1 belongs to the Sp1 C2H2-type zinc-finger protein family. It contains 3 C2H2-type zinc fingers. SP1 binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. It can interact with G/C-rich motifs from serotonin receptor promoter.
Protein Interaction Partner: JUN, UBC, HIC1, HDAC1, SP3, TP53, CTNNB1, ARHGAP21, SENP6, C3orf17, USP39, FOXM1, ESR1, DDX5, KIF1A, PPIG, TPI1, TFAP2A, NAP1L1, HDAC2, NUP62, MYC, HIF1A, POU2F1, SMAD3, DDX3X, TBP, SP1, RBL1, Taf4, tat, ESR2, VHL, YY1, CASP7, CASP6, CASP3, HTT, BRCA1, MA
Protein Size: 737
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Molecular Weight
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75 kDa
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Gene ID
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6667
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UniProt
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E4Z9M7
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Pathways
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Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
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