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FCGR1A antibody

FCGR1A Reactivity: Human FACS, IHC, Func Host: Mouse Monoclonal 10-1 unconjugated
Catalog No. ABIN2567892
  • Target See all FCGR1A Antibodies
    FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))
    Reactivity
    • 101
    • 25
    • 19
    • 13
    • 6
    • 5
    • 4
    • 4
    • 4
    • 1
    Human
    Host
    • 67
    • 39
    • 1
    Mouse
    Clonality
    • 65
    • 40
    • 2
    Monoclonal
    Conjugate
    • 38
    • 13
    • 12
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FCGR1A antibody is un-conjugated
    Application
    • 75
    • 61
    • 31
    • 25
    • 18
    • 16
    • 9
    • 9
    • 7
    • 6
    • 6
    • 3
    • 3
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    • 1
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    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Functional Studies (Func)
    Specificity
    The 15.2 antibody reacts with the 85-110 kDa intracellular adhesion molecule-1 (ICAM-1), a member of the Ig superfamily which acts as a ligand for the Lymphocyte Function-Associated Antigen-1 (LFA-1).
    Purification
    The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
    Clone
    10-1
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product FCGR1A Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Phosphate-buffered aqueous solution, ph7.2.
    Storage
    4 °C
    Storage Comment
    The product should be stored undiluted at 4°C. Do not freeze.
  • Target
    FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))
    Alternative Name
    CD64 (FCGR1A Products)
    Synonyms
    CD64 antibody, CD64A antibody, FCRI antibody, IGFR1 antibody, FcgammaRI antibody, Fcgr1 antibody, Fcgr1b antibody, AI323638 antibody, AV092959 antibody, IGGHAFC antibody, FCGR1A antibody, Fc fragment of IgG receptor Ia antibody, Fc receptor, IgG, high affinity I antibody, FCGR1A antibody, Fcgr1a antibody, Fcgr1 antibody
    Background
    The 10.1 monoclonal antibody specifically reacts with human CD64, a 75kDA type I transmembrane glycoprotein that is the high affinity receptor for IgG. CD64 is expressed on macrophages and dendritic cells and is involved in antibody-dependent cellular toxicity, cytokine release phagocytosis, and endocytosis. The 10.1 antibody is reported to recognize the EC3 epitope of CD64.
    Gene ID
    2209
    UniProt
    P12314
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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