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FAS antibody

FAS Reactivity: Human FACS, Func Host: Mouse Monoclonal EOS9-1 unconjugated
Catalog No. ABIN2568064
  • Target See all FAS Antibodies
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    Reactivity
    • 208
    • 66
    • 62
    • 19
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 156
    • 86
    • 4
    • 2
    • 1
    • 1
    • 1
    Mouse
    Clonality
    • 156
    • 93
    • 1
    Monoclonal
    Conjugate
    • 116
    • 27
    • 25
    • 12
    • 11
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FAS antibody is un-conjugated
    Application
    • 160
    • 113
    • 73
    • 64
    • 35
    • 33
    • 27
    • 26
    • 26
    • 18
    • 16
    • 9
    • 8
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Functional Studies (Func)
    Specificity
    The EOS9.1 monoclonal antibody specifically reacts with human CD95, a 45 kDA type I membrane molecule. CD95 is a member of the tumor necrosis factor receptor (TNF-R) family and is involved in the mechanisms that lead to cellular apoptosis.
    Purification
    The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
    Clone
    EOS9-1
    Isotype
    IgM kappa
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    Discover our top product FAS Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Phosphate-buffered aqueous solution, ph7.2.
    Storage
    4 °C
    Storage Comment
    The product should be stored undiluted at 4°C. Do not freeze.
  • Target
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    Alternative Name
    CD95 (FAS Products)
    Synonyms
    ALPS1A antibody, APO-1 antibody, APT1 antibody, CD95 antibody, FAS1 antibody, FASTM antibody, TNFRSF6 antibody, AI196731 antibody, APO1 antibody, TNFR6 antibody, Tnfrsf6 antibody, lpr antibody, Fas cell surface death receptor antibody, Fas (TNF receptor superfamily member 6) antibody, FAS antibody, Fas antibody, fas antibody
    Background
    The EOS9.1 monoclonal antibody specifically reacts with human CD95, a 45 kDA type I membrane molecule. CD95 is a member of the tumor necrosis factor receptor (TNF-R) family and is involved in the mechanisms that lead to cellular apoptosis. It is expressed on fibroblasts, monocytes, lymphocytes, and neutrophils. CD95 induces apoptosis after binding with CD178 or Fas ligand and the EOS9.1 antibody is reported to be used for inducing apoptosis in Fas-positive cells.
    Gene ID
    355
    UniProt
    P25445
    Pathways
    p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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