MYT1 antibody (pSer83)

Catalog No. ABIN2568374

Product Details anti-MYT1 Antibody

Target: MYT1 (Myelin Transcription Factor 1 (MYT1))

Binding Specificity: pSer83

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYT1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Specificity: The antibody detects endogenous levels of MYT1 only when phosphorylated at serine 83.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: MYT1 (phospho Ser83) antibody was raised against a peptide sequence around phosphorylation site of Serine 83 (R-V-S (p)-F-R) derived from Human MYT1.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for MYT1

Target: MYT1 (Myelin Transcription Factor 1 (MYT1))

Alternative Name: MYT1 (MYT1 Products)

Synonyms: fc56h05 antibody, myt1 antibody, si:dkey-202m22.5 antibody, wu:fc56h05 antibody, C20orf36 antibody, MTF1 antibody, MYTI antibody, PLPB1 antibody, ZC2HC4A antibody, Nzf2 antibody, Nzf2a antibody, Nzf2b antibody, Nztf2 antibody, myelin transcription factor 1 antibody, myelin transcription factor 1a antibody, myelin transcription factor 1 S homeolog antibody, MYT1 antibody, myt1a antibody, Myt1 antibody, myt1.S antibody

Background: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Molecular Weight: 54 kDa

Gene ID: 9088

NCBI Accession: XP_006721039

UniProt: Q99640

Pathways: Cell Division Cycle