Notch1 antibody (PE)
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- Target See all Notch1 (NOTCH1) Antibodies
- Notch1 (NOTCH1) (Notch 1 (NOTCH1))
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Reactivity
- Human, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Notch1 antibody is conjugated to PE
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Application
- Flow Cytometry (FACS)
- Specificity
- The mN1A monoclonal antibody reacts with the intracellular domain of human and mouse Notch1 with high affinity for the activated intracellular form and lower affinity for the full length heterodimeric Notch1 forms.
- Purification
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- Clone
- MN1A
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product NOTCH1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.2 mg/mL
- Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
- Storage
- 4 °C
- Storage Comment
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- Target
- Notch1 (NOTCH1) (Notch 1 (NOTCH1))
- Alternative Name
- Notch1 (NOTCH1 Products)
- Synonyms
- notch1 antibody, NOTCH1 antibody, hn1 antibody, tan1 antibody, notch antibody, xotch antibody, xnotch antibody, notch-1 antibody, xnotch1 antibody, TAN1 antibody, hN1 antibody, 9930111A19Rik antibody, Mis6 antibody, N1 antibody, Tan1 antibody, lin-12 antibody, NOTCH antibody, Xotch antibody, notch1-a antibody, notch 1 antibody, fibropellin-1 antibody, Notch homolog 1, translocation-associated (Drosophila) antibody, Notch homolog 1, translocation-associated antibody, notch 1 S homeolog antibody, notch1 antibody, LOC100631526 antibody, NOTCH1 antibody, Notch1 antibody, notch1.S antibody
- Background
- The mN1A monoclonal antibody reacts with the intracellular domain of human and mouse Notch1 with high affinity for the activated intracellular form and lower affinity for the full length heterodimeric Notch1 forms. It does not react with Notch2,3, or 4 and does not cross-react with rat thymocytes. The neurogenic locus homolog protein 1 (Notch1) is a trasmembrane receptor that regulates cell fate decisions. It is expressed in CD4-CD8- and CD4-CD8+ thymocytes, and plays a role in the regulation of myelopoiesis and lymphopoiesis.
- Gene ID
- 4851, 18128
- UniProt
- P46531, Q01705
- Pathways
- Notch Signaling, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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