TAL1 antibody (pSer122)
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- Target See all TAL1 Antibodies
- TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))
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Binding Specificity
- pSer122
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TAL1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- The antibody detects endogenous levels of TAL-1 only when phosphorylated at serine 122.
- Purification
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Immunogen
- TAL-1 (phospho Ser122) antibody was raised against a peptide sequence around phosphorylation site of Serine 122 (Q-L-S (p)-P-P) derived from Human TAL-1.
- Isotype
- IgG
- Top Product
- Discover our top product TAL1 Primary Antibody
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- Application Notes
- Western Blot: 1:500~1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store antibody at -20°C for up to one year.
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- Target
- TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))
- Alternative Name
- TAL-1 (TAL1 Products)
- Synonyms
- SCL/tal-1 antibody, Scl antibody, bHLHa17 antibody, tal-1 antibody, SCL antibody, TCL5 antibody, scl antibody, tcl5 antibody, SCL-alpha antibody, SCL-beta antibody, scl/tal1 antibody, zgc:85605 antibody, T cell acute lymphocytic leukemia 1 antibody, TAL bHLH transcription factor 1, erythroid differentiation factor antibody, T-cell acute lymphocytic leukemia 1 S homeolog antibody, T-cell acute lymphocytic leukemia 1 antibody, Tal1 antibody, TAL1 antibody, tal1.S antibody, tal1 antibody
- Background
- TAL-1 is a basic helix-loop-helix transcription. Regulates differentiation and survival during hemopoiesis. Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. Binds to the LIM domain containing protein Rhombotin-2.
- Molecular Weight
- 45 kDa
- Gene ID
- 6886
- NCBI Accession
- NP_001274276
- UniProt
- P17542
- Pathways
- Stem Cell Maintenance
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