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FLT1 antibody (pTyr1048)
FLT1
Reactivity: Human, Rat, Mouse
IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-FLT1 Antibody
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Target
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FLT1
(Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
Binding Specificity
All epitopes for FLT1 antibodies
pTyr1048
Reactivity
All reactivities for FLT1 antibodies
Human, Rat, Mouse
Host
All hosts for FLT1 antibodies
Rabbit
Clonality
All clonalities for FLT1 antibodies
Polyclonal
Conjugate
All conjugates for FLT1 antibodies
This FLT1 antibody is un-conjugated
Application
All applications for FLT1 antibodies
Immunohistochemistry (IHC)
Specificity
The antibody detects endogenous levels of VEGFR1 only when phosphorylated at tyrosine 1048.
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Immunogen
VEGFR1 (phospho Tyr1048) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1048 (D-I-Y (p)-K-N) derived from Human VEGFR1.
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store antibody at -20°C for up to one year.
Target Details for FLT1
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Target
FLT1
(Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
Alternative Name
VEGFR1 (FLT1 Products )
Synonyms
FLT antibody, FLT-1 antibody, VEGFR-1 antibody, VEGFR1 antibody, FLT1 antibody, flt1b antibody, sFlt1 antibody, AI323757 antibody, Flt-1 antibody, fms related tyrosine kinase 1 antibody, FMS-related tyrosine kinase 1 antibody, vascular endothelial growth factor receptor 1 antibody, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) antibody, FMS-like tyrosine kinase 1 antibody, vascular endothelial growth factor receptor-1 antibody, FLT1 antibody, Flt1 antibody, CpipJ_CPIJ012087 antibody, flt1 antibody, FLT-1 antibody
Background
Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.
Molecular Weight
150 kDa
Gene ID
2321
NCBI Accession
NP_002010
UniProt
P17948
Pathways
RTK Signaling , Signaling Events mediated by VEGFR1 and VEGFR2 , VEGFR1 Specific Signals
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