BIRC3 antibody (AA 101-111)

Catalog No. ABIN2617576

Product Details anti-BIRC3 Antibody

Target: BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

Binding Specificity: AA 101-111

Reactivity: Human, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This BIRC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human BIRC3 / cIAP2. Reported variants represent identical protein: NP_892007.1, NP_001156.1.

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-SVNNLEATSQP from an internal region of human BIRC3 / cIAP2 (NP_001156.1). Percent identity by BLAST analysis: Human, Gibbon, Marmoset (100%), Monkey (91%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), Peptide-ELISA (1:16000), WB (1 - 3 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Experiments gave bands at approx 70kD and 52kD in Rat Testis lysates. These bands correspond to earlier findings with different antibodies from other commercial sources. This protein has a calculated MW of 67.3kD according to Rat NP_076477.2. Recommended concentration: 1-3 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for BIRC3

Target: BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

Alternative Name: BIRC3 / cIAP2 (BIRC3 Products)

Synonyms: AIP1 antibody, API2 antibody, CIAP2 antibody, HAIP1 antibody, HIAP1 antibody, MALT2 antibody, MIHC antibody, RNF49 antibody, c-IAP2 antibody, Api1 antibody, Api2 antibody, IAP1 antibody, IAP2 antibody, MIHB antibody, Birc2 antibody, HIAP2 antibody, MIAP1 antibody, MIAP2 antibody, cIAP1 antibody, cIAP2 antibody, cIAP-1 antibody, cIAP-2 antibody, AW107670 antibody, BIRC2 antibody, baculoviral IAP repeat containing 3 antibody, baculoviral IAP repeat-containing 3 antibody, baculoviral IAP repeat-containing protein 3 antibody, inhibitor of apoptosis protein-2 antibody, BIRC3 antibody, Birc3 antibody, LOC100399118 antibody, OpmnVgp074 antibody

Background: Name/Gene ID: BIRC3
Family: Apoptosis

Synonyms: BIRC3, AIP1, API2, Apoptosis inhibitor 2, CIAP2, Hiap-1, HIAP1, IAP homolog C, Mammalian IAP homolog C, MIHC, IAP-1, IAP1, RING finger protein 49, RNF49, C-IAP2, HAIP1, MALT2

Gene ID: 330

NCBI Accession: NP_001156

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades