CD177 antibody

Catalog No. ABIN2689019

Product Details anti-CD177 Antibody

Target: CD177 (CD177 Molecule (CD177))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD177 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Brand: BD Pharmingen™

Characteristics: Reacts with the GPI-anchored plasma membrane glycoprotein (56-64 kDa) neutrophil-specific antigen NB1. CD177 is expressed on neutrophils, neutrophillic metamyelocytes and myelocytes from 89 to 97 % of healthy individuals. Its expression is upregulated on granulocytes stimulated with the chemotactic peptide f-met-leu-phe (fMLP). The function of CD177 has not been fully elucidated at this time, however, some findings suggest its possible role as receptor molecule. Profile of peripheral blood granulocytes analyzed by flow cytometry. Second step staining with Cat. No. 555988.

BD Pharmingen™ Purified Mouse Anti-Human CD177 - Purified - Clone MEM-166 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: MEM

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-CD177 antibody (ABIN2689019)

Matsuo, Lin, Procter, Clement, Stroncek: "Variations in the expression of granulocyte antigen NB1." in: Transfusion, Vol. 40, Issue 6, pp. 654-62, (2000) (PubMed).

Stroncek, Shankar, Litz, Clement: "The expression of the NB1 antigen on myeloid precursors and neutrophils from children and umbilical cords." in: Transfusion medicine (Oxford, England), Vol. 8, Issue 2, pp. 119-23, (1998) (PubMed).

Stroncek, Shankar, Noren, Herr, Clement: "Analysis of the expression of NB1 antigen using two monoclonal antibodies." in: Transfusion, Vol. 36, Issue 2, pp. 168-74, (1996) (PubMed).

Clement, Lehmeyer, Gartland: "Identification of neutrophil subpopulations with monoclonal antibodies." in: Blood, Vol. 61, Issue 2, pp. 326-32, (1983) (PubMed).

Target Details for CD177

Target: CD177 (CD177 Molecule (CD177))

Alternative Name: CD177 (CD177 Products)

Synonyms: HNA-2a antibody, HNA2A antibody, NB1 antibody, NB1 GP antibody, PRV-1 antibody, PRV1 antibody, RGD1562941 antibody, CD177 antibody, MGC157159 antibody, 1190003K14Rik antibody, Pdp3 antibody, CD177 molecule antibody, CD177 antigen antibody, CD177 antibody, Cd177 antibody

Background: Synonyms: NB1