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IL12 antibody (Biotin)

IL12 Reactivity: Mouse WB, ELISA, IP Host: Rat Monoclonal C17-8 Biotin
Catalog No. ABIN2689728
  • Target See all IL12 Antibodies
    IL12 (Interleukin 12 (IL12))
    Reactivity
    • 47
    • 18
    • 16
    • 7
    • 4
    • 2
    • 1
    • 1
    Mouse
    Host
    • 32
    • 26
    • 15
    • 11
    • 2
    Rat
    Clonality
    • 47
    • 35
    Monoclonal
    Conjugate
    • 36
    • 14
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This IL12 antibody is conjugated to Biotin
    Application
    • 67
    • 53
    • 26
    • 26
    • 14
    • 11
    • 10
    • 8
    • 7
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    Brand
    BD Pharmingen™
    Characteristics
    The C17.8 antibody reacts with the free p40 monomer of IL-12 as well as the p40 subunit complexed as homodimer or complexed with p35 as a p70 heterodimer.

    BD Pharmingen™ Biotin Rat Anti-Mouse IL-12 (p40/p70) - Biotin - Clone C17.8 - Isotype Rat IgG2a - Reactivity Ms - 0.5 mg
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Recombinant Mouse IL-12 p70
    Clone
    C17-8
    Isotype
    IgG2a
    Top Product
    Discover our top product IL12 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
    Storage
    4 °C
    Storage Comment
    Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
  • Neurath, Fuss, Kelsall, Stüber, Strober: "Antibodies to interleukin 12 abrogate established experimental colitis in mice." in: The Journal of experimental medicine, Vol. 182, Issue 5, pp. 1281-90, (1995) (PubMed).

    Wysocka, Kubin, Vieira, Ozmen, Garotta, Scott, Trinchieri: "Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice." in: European journal of immunology, Vol. 25, Issue 3, pp. 672-6, (1995) (PubMed).

    DAndrea, Rengaraju, Valiante, Chehimi, Kubin, Aste, Chan, Kobayashi, Young, Nickbarg: "Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells." in: The Journal of experimental medicine, Vol. 176, Issue 5, pp. 1387-98, (1992) (PubMed).

  • Target
    IL12 (Interleukin 12 (IL12))
    Alternative Name
    IL-12 p40,p70 (IL12 Products)
    Synonyms
    CLMF antibody, CLMF2 antibody, IL-12B antibody, NKSF antibody, NKSF2 antibody, p40 antibody, Il-12b antibody, Il12p40 antibody, Il-12p40 antibody, Il12 antibody, IL-12p40 antibody, IL-12 antibody, LOC100217488 antibody, IL-12p35 antibody, Il-12a antibody, Ll12a antibody, p35 antibody, IL12p40 antibody, IL12B antibody, IL-12 p35 antibody, interleukin 12B antibody, interleukin 12A antibody, interleukin 12b antibody, interleukin 12a antibody, Interleukin 12 level antibody, IL12B antibody, IL12A antibody, Il12b antibody, Il12a antibody, IL12 antibody, il12a antibody
    Pathways
    JAK-STAT Signaling, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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