RAD51 Homolog B antibody (AA 119-346)

Catalog No. ABIN2730412

Product Details anti-RAD51 Homolog B Antibody

Target: RAD51 Homolog B (Rad51B)

Binding Specificity: AA 119-346

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RAD51 Homolog B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Characteristics: Homo sapiens RAD51 homolog B (S. cerevisiae) (RAD51B), transcript variant 3

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Human recombinant protein fragment corresponding to amino acids 119-346 of human RAD51L1(NP_598193) produced in E.coli.

Clone: 7H4

Isotype: IgG1

Application Details

Application Notes: WB 1:500, IF 1:100, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for RAD51 Homolog B

Target: RAD51 Homolog B (Rad51B)

Alternative Name: RAD51L1 (Rad51B Products)

Synonyms: R51H2 antibody, RAD51L1 antibody, REC2 antibody, AI553500 antibody, Rad51l1 antibody, mREC2 antibody, ATRAD51B antibody, T17D12.12 antibody, T17D12_12 antibody, RGD1560681 antibody, rad51l1 antibody, wu:fd07f04 antibody, zgc:56581 antibody, RAD51 paralog B antibody, DNA repair (Rad51) family protein antibody, Rad51 DNA recombinase 2 antibody, RAD51B antibody, Rad51b antibody, rad51b antibody

Background: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.

Molecular Weight: 42 kDa

Gene ID: 5890

NCBI Accession: NM_133509

HGNC: 5890

Pathways: DNA Damage Repair