RFC2 antibody
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- Target See all RFC2 Antibodies
- RFC2 (Replication Factor C (Activator 1) 2, 40kDa (RFC2))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This RFC2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- Homo sapiens replication factor C (activator 1) 2, 40 kDa (RFC2), transcript variant 2
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of huamn RFC2(NP_002905) produced in E.coli.
- Clone
- 3F6
- Isotype
- IgG1
- Top Product
- Discover our top product RFC2 Primary Antibody
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- Application Notes
- WB 1:2000, IHC 1:150,
- Comment
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- RFC2 (Replication Factor C (Activator 1) 2, 40kDa (RFC2))
- Alternative Name
- RFC2 (RFC2 Products)
- Synonyms
- 2610008M13Rik antibody, 40kDa antibody, AI326953 antibody, Recc2 antibody, RFC40 antibody, replication factor C subunit 2 antibody, replication factor C (activator 1) 2 antibody, LOC100231971 antibody, RFC2 antibody, Rfc2 antibody
- Background
- The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also called activator 1, is a protein complex consisting of five distinct subunits of 145, 40, 38, 37, and 36.5 kD. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP. Deletion of this gene has been associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described.
- Molecular Weight
- 35.1 kDa
- Gene ID
- 5982
- NCBI Accession
- NM_002914
- HGNC
- 5982
- Pathways
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
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