AKT1 antibody (pSer473)

Catalog No. ABIN273317

The Rabbit Polyclonal anti-AKT1 antibody has been validated for WB and IHC. It is suitable to detect AKT1 in samples from Human, Mouse and Rat. There are 4+ publications available.

Quick Overview for AKT1 antibody (pSer473) (ABIN273317)

Target: AKT1 (V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-AKT1 Antibody

Binding Specificity: pSer473

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

References for anti-AKT1 antibody (ABIN273317)

Jiao, Fan, Wang, Zhang, Chen, Chen: "Protective Effect and Mechanism of Total Flavones from Rhododendron simsii Planch Flower on Cultured Rat Cardiomyocytes with Anoxia and Reoxygenation." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 863531, (2015) (PubMed).

Zhang, Zhang, Liu, Hao, Wang, Li, Yin, Liang: "Secreted clusterin gene silencing enhances chemosensitivity of a549 cells to cisplatin through AKT and ERK1/2 pathways in vitro." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 33, Issue 4, pp. 1162-75, (2014) (PubMed).

Chen, Wu, Shi, Wang, Zhang, Cao, Jiang, Ding: "Hepatic stellate cell coculture enables sorafenib resistance in Huh7 cells through HGF/c-Met/Akt and Jak2/Stat3 pathways." in: BioMed research international, Vol. 2014, pp. 764981, (2014) (PubMed).

Ci, Shi, An, Yang, Hui, Wu, Shi, Xu: "ROS inhibit autophagy by downregulating ULK1 mediated by the phosphorylation of p53 in selenite-treated NB4 cells." in: Cell death & disease, Vol. 5, pp. e1542, (2014) (PubMed).

Target Details for AKT1

Target: AKT1 (V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1))

Alternative Name: Akt

UniProt: P31749

Pathways: PI3K-Akt Signaling, RTK Signaling, TCR Signaling, AMPK Signaling, Interferon-gamma Pathway, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Water Deprivation, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGFR1 Specific Signals, VEGF Signaling, Warburg Effect