CD2 antibody

Catalog No. ABIN2739096

Product Details anti-CD2 Antibody

Target: CD2

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Specificity: Human CD2

Purification: Protein G purified

Immunogen: Human CD2 protein.

Type of Immunogen: Purified protein

Clone: BH1

Isotype: IgG2b kappa

Application Details

Application Notes: Approved: Flo (0.5 - 1 μg/10 x10⁶), IF (0.5 - 1 μg/mL)

Usage: CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells. ELISA: Order BSA-free format for coating.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C to 8°C.

Target Details for CD2

Target: CD2

Alternative Name: CD2 (CD2 Products)

Synonyms: CD2 antibody, LFA-2 antibody, Ly-37 antibody, Ly37 antibody, SRBC antibody, T11 antibody, CD2R antibody, LFA2 antibody, OX-34 antibody, OX34 antibody, CD2 molecule antibody, CD2 antigen antibody, Cd2 molecule antibody, CD2 antibody, Cd2 antibody

Background: Name/Gene ID: CD2

Synonyms: CD2, CD2 antigen, Erythrocyte receptor, LFA-3 receptor, LFA-2, Lymphocyte-function antigen-2, T11, SRBC, CD2 Molecule, Rosette receptor, T-cell surface antigen CD2

Gene ID: 914