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FAS antibody

FAS Reactivity: Human WB, FACS, IP, Func Host: Mouse Monoclonal APO-1-3 unconjugated
Catalog No. ABIN2745529
  • Target See all FAS Antibodies
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    Reactivity
    • 207
    • 66
    • 62
    • 19
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 156
    • 85
    • 4
    • 2
    • 1
    • 1
    • 1
    Mouse
    Clonality
    • 156
    • 92
    • 1
    Monoclonal
    Conjugate
    • 115
    • 27
    • 25
    • 12
    • 11
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FAS antibody is un-conjugated
    Application
    • 159
    • 112
    • 73
    • 64
    • 34
    • 33
    • 27
    • 26
    • 26
    • 18
    • 16
    • 8
    • 8
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
    Specificity
    Recognizes human Fas.
    Cross-Reactivity
    Human
    Purity
    >95 % (SDS-PAGE)
    Immunogen
    Recombinant human Fas.
    Clone
    APO-1-3
    Isotype
    IgG3
    Top Product
    Discover our top product FAS Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    In PBS.
    Preservative
    Without preservative
    Storage
    4 °C,-20 °C
    Storage Comment
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Expiry Date
    12 months
  • Target
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    Alternative Name
    Fas (FAS Products)
    Synonyms
    ALPS1A antibody, APO-1 antibody, APT1 antibody, CD95 antibody, FAS1 antibody, FASTM antibody, TNFRSF6 antibody, AI196731 antibody, APO1 antibody, TNFR6 antibody, Tnfrsf6 antibody, lpr antibody, Fas cell surface death receptor antibody, Fas (TNF receptor superfamily member 6) antibody, FAS antibody, Fas antibody, fas antibody
    Background
    Fas (CD95) is a member of the death receptor (DR) family, a subfamily of the tumor necrosis factor receptor superfamily. The formation of the Fas death-inducing signaling complex (DISC) is the initial step of Fas signaling. Activation of procaspase-8 at the DISC leads to the induction of DR-mediated apoptosis. Stimulation of Fas has been also reported to trigger non-apoptotic pathways. It has been shown that membrane-bound FasL is essential for the cytotoxic activity, whereas soluble FasL appears to promote autoimmunity and tumorigenesis via induction of non-apoptotic pathways, in particular NF-kappaB.
    UniProt
    P25445
    Pathways
    p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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