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Podoplanin antibody

PDPN Reactivity: Human WB, IHC, FACS Host: Mouse Monoclonal 18H5 unconjugated
Catalog No. ABIN2745556
  • Target See all Podoplanin (PDPN) Antibodies
    Podoplanin (PDPN)
    Reactivity
    • 78
    • 22
    • 4
    • 3
    • 1
    Human
    Host
    • 54
    • 24
    • 7
    • 5
    • 2
    • 2
    • 1
    Mouse
    Clonality
    • 50
    • 45
    Monoclonal
    Conjugate
    • 53
    • 10
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Podoplanin antibody is un-conjugated
    Application
    • 70
    • 33
    • 31
    • 25
    • 20
    • 16
    • 14
    • 8
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Specificity
    Recognizes human podoplanin.
    Cross-Reactivity
    Human
    Purification
    Protein G purified.
    Immunogen
    MDCK cells stably expressing podoplanin.
    Clone
    18H5
    Isotype
    IgG1
    Top Product
    Discover our top product PDPN Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge vial prior to opening. Reconstitute with sterile water to a concentration of 0.1-1.0 mg/mL.
    Concentration
    Lot specific
    Buffer
    Lyophilized.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Expiry Date
    6 months
  • Target
    Podoplanin (PDPN)
    Alternative Name
    Podoplanin (PDPN Products)
    Synonyms
    PDPN antibody, AGGRUS antibody, GP36 antibody, GP40 antibody, Gp38 antibody, HT1A-1 antibody, OTS8 antibody, PA2.26 antibody, T1A antibody, T1A-2 antibody, OTS-8 antibody, RANDAM-2 antibody, T1-alpha antibody, T1a antibody, T1alpha antibody, E11 antibody, RTI40 antibody, podoplanin antibody, PDPN antibody, Pdpn antibody
    Background
    Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma and brain tumors. Podoplanin is the ligand for C-type lectin-like receptor 2 (CLEC-2). Their association is dependent on sialic acid on O-glycans of podoplanin. Through its association with CLEC-2, podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.
    Pathways
    Dicarboxylic Acid Transport
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