DACT1 antibody (Middle Region)
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- Target See all DACT1 Antibodies
- DACT1 (Dapper, Antagonist of beta-Catenin, Homolog 1 (DACT1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Zebrafish (Danio rerio), Guinea Pig, Rabbit, Cow, Dog, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DACT1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LSLVQKKTHP VRTNKPRTSV NADPTKGLLR NGSVCVRAPG GVSQGNSVNL
- Predicted Reactivity
- Cow: 100%, Dog: 93%, Guinea Pig: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%, Zebrafish: 85%
- Characteristics
- This is a rabbit polyclonal antibody against DACT1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product DACT1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 836 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- DACT1 (Dapper, Antagonist of beta-Catenin, Homolog 1 (DACT1))
- Alternative Name
- DACT1 (DACT1 Products)
- Synonyms
- XDpr antibody, dpr1 antibody, frodo antibody, hdpr1 antibody, Dapper antibody, thyex3 antibody, dapper1 antibody, MGC89695 antibody, frd1 antibody, frodo1 antibody, 4921528D17Rik antibody, AI115603 antibody, DAPPER antibody, DAPPER1 antibody, FRODO antibody, Frd1 antibody, Frodo1 antibody, MDpr1 antibody, MTNG3 antibody, THYEX3 antibody, DPR1 antibody, HDPR1 antibody, DACT1 antibody, RGD1564008 antibody, XDpr1a antibody, dact1 antibody, dpr antibody, XDpr1b antibody, dishevelled-binding antagonist of beta-catenin 1 antibody, dishevelled binding antagonist of beta catenin 1 antibody, dishevelled-binding antagonist of beta-catenin 1 L homeolog antibody, dishevelled-binding antagonist of beta-catenin 1 S homeolog antibody, dact1 antibody, Dact1 antibody, DACT1 antibody, dact1.L antibody, dact1.S antibody
- Background
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DACT1 positively regulates DVL2-mediated signaling pathways during development. It binds to DVL2 and impedes the degradation of CTNNB1/beta-catenin, thereby enhancing the transcriptional activation of target genes of the Wnt signaling pathway.
Alias Symbols: DAPPER, DAPPER1, DPR1, FRODO, HDPR1, THYEX3
Protein Interaction Partner: BECN1, PIK3C3, ATG14, CBX6, PPP1CC, Dact1, Dact3, C7orf25, TK1, SH3GL2, CSNK2B, LEF1, HDAC1,
Protein Size: 836 - Molecular Weight
- 92 kDa
- Gene ID
- 51339
- NCBI Accession
- NM_016651, NP_057735
- UniProt
- Q9NYF0
- Pathways
- Positive Regulation of fat Cell Differentiation
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