CD82 antibody (Middle Region)

Catalog No. ABIN2774369

Product Details anti-CD82 Antibody

Target: CD82

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD82 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ELIRDYNSSR EDSLQDAWDY VQAQVKCCGW VSFYNWTDNA ELMNRPEVTY

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CD82. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of CD82

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 242 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD82

Target: CD82

Alternative Name: CD82 (CD82 Products)

Synonyms: AA682076 antibody, AL023070 antibody, C33 antibody, IA4 antibody, Kai1 antibody, Tspan27 antibody, 4F9 antibody, GR15 antibody, KAI1 antibody, R2 antibody, SAR2 antibody, ST6 antibody, TSPAN27 antibody, CD82 antigen antibody, CD82 molecule antibody, Cd82 molecule antibody, Cd82 antibody, CD82 antibody

Background: This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: 4F9, C33, GR15, IA4, KAI1, R2, SAR2, ST6, TSPAN27
Protein Interaction Partner: GGT1, CD81, CD53, UBC, LGALS3BP, AMFR, VANGL1, IGSF8, ITGA3, NUP88, PTGFRN, ITGB2, ITGA4, ERBB3, CD4, ERBB2, CD63, ITGA6, HLA-DRA, HLA-DMB, HLA-DMA, ITGB1, EGFR, HBEGF, CANX, LRP1, CD19, ITGAL, HLA-DOB, CD46, CD151, CD9, RUVBL1, POLR2A, KAT5, CTNNB1, RUVB
Protein Size: 242

Molecular Weight: 27 kDa

Gene ID: 3732

NCBI Accession: NM_001024844, NP_001020015

UniProt: P27701

Pathways: p53 Signaling