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ARNT antibody (Middle Region)
ARNT
Reactivity: Human, Mouse, Rat, Cow, Rabbit, Sheep, Guinea Pig, Horse, Dog, Zebrafish (Danio rerio)
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ARNT Antibody
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Target
See all ARNT Antibodies
ARNT
(Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))
Binding Specificity
All epitopes for ARNT antibodies
Middle Region
Reactivity
All reactivities for ARNT antibodies
Human, Mouse, Rat, Cow, Rabbit, Sheep, Guinea Pig, Horse, Dog, Zebrafish (Danio rerio)
Host
All hosts for ARNT antibodies
Rabbit
Clonality
All clonalities for ARNT antibodies
Polyclonal
Conjugate
All conjugates for ARNT antibodies
This ARNT antibody is un-conjugated
Application
All applications for ARNT antibodies
Western Blotting (WB)
Sequence
QSSADKERLA RENHSEIERR RRNKMTAYIT ELSDMVPTCS ALARKPDKLT
Predicted Reactivity
Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 93%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 93%, Zebrafish: 93%
Characteristics
This is a rabbit polyclonal antibody against ARNT. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human ARNT
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Alternatives
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Application Details
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Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for ARNT
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Target
ARNT
(Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))
Alternative Name
ARNT (ARNT Products )
Synonyms
HIF-1-beta antibody, HIF-1beta antibody, HIF1-beta antibody, HIF1B antibody, HIF1BETA antibody, TANGO antibody, bHLHe2 antibody, D3Ertd557e antibody, Drnt antibody, ESTM42 antibody, Hif1b antibody, W08714 antibody, mKIAA4051 antibody, Arnt1 antibody, ARNT antibody, zgc:136664 antibody, arnt1 antibody, hif1b antibody, tango antibody, xArnt antibody, hif1beta antibody, hif-1beta antibody, arnt.2 antibody, MGC68805 antibody, aryl hydrocarbon receptor nuclear translocator antibody, aryl hydrocarbon receptor nuclear translocator S homeolog antibody, ARNT antibody, Arnt antibody, arnt antibody, arnt.S antibody
Background
This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. Alias Symbols: HIF1B, TANGO, bHLHe2, HIF1BETA, HIF-1beta, HIF1-beta, HIF-1-beta Protein Size: 416
Molecular Weight
45 kDa
Gene ID
405
NCBI Accession
NM_001197325 , NP_001184254
UniProt
P27540
Pathways
Regulation of Hormone Metabolic Process , Regulation of Hormone Biosynthetic Process , Regulation of Carbohydrate Metabolic Process , Signaling Events mediated by VEGFR1 and VEGFR2 , Warburg Effect
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